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Electrobiome┬«: Microbial Production of Chemicals & Fuels from CO┬Č2
The inventors have developed an electrosynthetic microbiome, called the Electrobiome®, which converts CO2, water, and electricity into hydrogen (H2), formic acid, and acetic acid. The Electrobiome® has been continually operating for more than four years and can operate with intermittent power, which demonstrates sustainability that far sur...
Published: 5/22/2017   |   Inventor(s): Harold May, Edward LaBelle
Category(s): Other
Bioremediation of Polychlorinated Biphenyls (PCBs)
The invention includes compositions and methods for bioremediation of PCBs using anaerobic microorganisms that remove chlorines from PCBs and aerobic microorganisms that then break down the remaining biphenyl rings. The PCB-degrading microorganisms are inoculated onto pellets called SediMite™ that contain activated carbon, sand and binder. Se...
Published: 9/28/2016   |   Inventor(s): Kevin Sowers, Harold May
Category(s): Other
Mitoferrofluor - A new approach to determine mitochondrial chelatable iron
Inventors have created a fluorescent marker, mitoferrofluor (MFF) for measuring mitochondrial chelatable iron in living cells and tissues. It is an improvement on existing markers, as it covalently bonds to the mitochondria once it has entered, thus it will remain there through any subsequent reactions. Iron is an essential nutrient. Incorporation...
Published: 7/26/2016   |   Inventor(s): John Lemasters, Andaleb Kholmukhamedov, Christopher Lindsey, Craig Beeson
Category(s): Other
3-D Biomimetic Technology to Create Defined Architectures in Hydrogels
Inventors have developed a biofabrication platform that can be tuned to mimic the native in vivo architecture and geometries vital to the physiological function of tissue. The inventors use a new material for molding intrinsic geometries to an in vitro collagen hydrogel by allowing the adequate transfer of the specific architectural features to a n...
Published: 1/7/2015   |   Inventor(s): Michael Yost, Veronica Rodriguez-Rivera
Category(s): Other
High-Throughput Screening Assay for Novel Inhibitors of Penicillin Binding Proteins
Researchers at MUSC have developed a high-throughput assay that uses fluorescence polarization (FP) to distinguish the fluorescent penicillin, Bocillin-FL, in free or PBP-bound form. The assay can be used to identify new compounds that inhibit penicillin binding proteins (PBPs), which are proven targets for β-lactam antibiotics. This assay wa...
Published: 9/25/2014   |   Inventor(s): Christopher Davies, Alena Fedarovich, Yuri Peterson
Keywords(s): infectious
Category(s): Therapeutic, Other
Pseudo-Diaphragmatic Expansion Perfusion & Cryopreservation of Intact Viable Tissues
Researchers at MUSC have developed a rapid and reproducible method for the cryopreservation of a variety of tissues, such that when thawed are comparable to freshly resected tissues. To date, analysis has been completed on lung tissue from patients undergoing lobectomy or transplant and prostate tissue. This method involves the pseudo-diaphragmatic...
Published: 5/16/2014   |   Inventor(s): John Baatz, Demetri D. Spyropoulos
Category(s): Other
Electrobiome: Microbial Production of Chemicals & Fuels from Carbon Dioxide
The inventors have developed an electrosynthetic microbiome, called the Electrobiome, that directly converts CO2, water, and electricity into hydrogen (H2), formic acid, and acetic acid. The Electrobiome can also produce polyesters (bioplastic), alcohols (ethanol, butanol), and is being developed further for the production of liquid hydrocarbons. ...
Published: 3/29/2013   |   Inventor(s): Harold May, Christopher Marshall, Edward LaBelle
Keywords(s): fuel cell
Category(s): Other
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