Search Results - david+cole

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Use of the KS1/4 Gene For Detection and/or Diagnosis of Lung Cancer
Technology: Inventors from MUSC have developed a reliable real-time RT-PCR method to detect metastatic non-small cell lung cancer (NSCLC) in mediastinal lymph nodes (MLNs) by endoscopic ultrasound guided fine-needle aspiration (EUS-FNA). This technique enables reliable biopsy of MLNs without the need for general surgery or anesthesia. Researchers tested...
Published: 3/4/2020   |   Inventor(s): Michael Mitas, David Cole, William Gillanders, Michael Wallace
Category(s): Diagnostic
Method of Enhanced Adoptive Cellular Therapy without Lymphodepletion
Technology: Lymphodepleting chemotherapy is a significant hurdle to the use of adoptive cellular therapy. MUSC researchers have found a method to overcome the need to provide lymphodepleting chemotherapy to patients receiving Adoptive Cellular Therapy (ACT) by endowing donor T cells with elevated levels of cytokine receptors to outcompete host cells...
Published: 11/13/2015   |   Inventor(s): Mark Rubinstein, David Cole
Category(s): Therapeutic
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