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Advancements of 599 peptide carrier design through stereochemical and/or amino acid modifications

Technology: Researchers at MUSC have developed a cell-penetrating peptide (CPP) specifically designed to overcome challenges associated with small interfering RNA (siRNA)-drug delivery for cancer treatment. Investigators previously generated the 599 peptide that silenced the CIP2A oncogene and suppressed tumor growth in vivo (Figure 1). Figure...

Published: 3/22/2023 | Inventor(s): Andrew Jakymiw, Charles Holjencin

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Category(s): BioPharma