Search Results - craig+kutz

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LSD1 Protein Inhibitors as Fetal Hemoglobin Inducers for Sickle Cell Disease
Technology: Researchers at MUSC have identified several potential inhibitors of lysine-specific demethylase 1 (LSD1) utilizing a virtual screen and found compounds that fit the LSD1 active site in silico. Next, they synthesized these molecules and evaluated them as highly selective LSD1 inhibitors. The series of compounds are new chemical entities being...
Published: 4/4/2017   |   Inventor(s): Patrick Woster, Craig Kutz
Keywords(s):  
Category(s): Therapeutic
LSD1 Protein Inhibitors as Cancer Therapeutics
Technology: Researchers at MUSC have identified several potential inhibitors of lysine-specific demethylase 1 (LSD1) utilizing a virtual screen and found compounds that fit the LSD1 active site in silico. LSD1 is overexposed in a number of human cancers (neuroblastoma, retinoblastoma, prostate, cancer, lung, and bladder), and has emerged as an important...
Published: 5/13/2014   |   Inventor(s): Patrick Woster, Craig Kutz
Keywords(s):  
Category(s): Therapeutic
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