Search Results - craig kutz

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LSD1 Protein Inhibitors as Fetal Hemoglobin Inducers for Sickle Cell Disease
Technology: Researchers at MUSC have identified several potential inhibitors of lysine-specific demethylase 1 (LSD1) utilizing a virtual screen, and found compounds that fit the LSD1 active site in silico. Researchers have synthesized these molecules and evaluated them as LSD1 inhibitors, and several compounds inhibit the enzyme with Ki values in t...
Published: 4/4/2017   |   Inventor(s): Patrick Woster, Craig Kutz
Keywords(s):  
Category(s): Therapeutic
LSD1 Protein Inhibitors as Cancer Therapeutics
Technology: Researchers at MUSC have identified several potential inhibitors of lysine-specific demethylase 1 (LSD1) utilizing a virtual screen, and found compounds that fit the LSD1 active site in silico. LSD1 is overexposed in a number of human cancers (neuroblastoma, retinoblastoma, prostate, cancer, lung, and bladder), and has emerged as an imp...
Published: 5/13/2014   |   Inventor(s): Patrick Woster, Craig Kutz
Keywords(s):  
Category(s): Therapeutic
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