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G9a inhibition decreases stress-induced escalation of alcohol drinking
Technology: Inventors at MUSC have identified that NAc (nucleus accumbens) G9a is requiredfor stress-regulated drinking in both ethanol-dependent and non-dependent animals.Importantly they discovered that treating mice with UNC0642 (an inhibitor of G9a) in a stressinducedethanol drinking assay (Figure. 1A) showed significant reduction in ethanol consumptionduring...
Published: 6/3/2021   |   Inventor(s): Ethan Anderson, Christopher Cowan
Category(s): Therapeutic
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