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Blocking GARP (LRRC32) cleavage and Its Application in Immunotherapy

Technology: Researchers at MUSC have developed a method and peptide composition (the “T250 peptide”) for treating cancer by inhibiting Glycoprotein-A Repetitions Predominant Protein (GARP) cleavage and thus impeding the activation of Transforming Growth Factor-Beta (TGF-β) – a growth factor that suppresses T-cell mediated anti-cancer...

Published: 4/29/2024 | Inventor(s): Zihai Li

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Category(s): BioPharma