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M1/Mdivi1 as a novel treatment to reduce immunogenicity in organ transplantation

Technology: Addition of M1 and Mdivi1 drugs in organ preservation solutions can reduce the immunogenicity of the donor organ’s microvascular endothelial cells (ECs), thereby promoting allograft immune tolerance. Inventors at MUSC have found that the use of M1 (a mitochondrial fusion promoter) and Mdivi1 (a mitochondrial fission inhibitor) as a...

Published: 3/23/2023 | Inventor(s): Satish Nadig, Carl Atkinson, Danh Tran

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Category(s): BioPharma