Search Results - carl atkinson

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Implantable Port for Cellular Therapies and Localized Drug Delivery
Implantable Port for Cellular Therapies and Localized Drug DeliveryTechnology: Researchers in a collaboration between MUSC and Clemson have created a revolutionary subcutaneous implantable port with the potential for use in a broad spectrum of treatments including cellular therapies and localized drug delivery.The device is comprised of a subdermal...
Published: 5/16/2018   |   Inventor(s): William Scammon, Alexander Ormerod, Lucas Tatem, Satish Nadig, Carl Atkinson, Jane Kilkenny
Category(s): Device
Organ Preconditioning with Mitochondrial Elongating Agents M1/Mdivi1 in Transplantation
M1/Mdivi1 as a novel treatment to reduce immunogenicity in organ transplantationTechnology: Addition of M1 and Mdivi1 drugs in organ preservation solutions can reduce the immunogenicity of the donor organ’s microvascular endothelial cells (ECs), thereby promoting allograft immune tolerance. Inventors at MUSC have found that the use of M1 (a m...
Published: 3/19/2018   |   Inventor(s): Satish Nadig, Carl Atkinson, Danh Tran
Category(s): Therapeutic
Targeted Rapamycin Micelle (TRaM) as a Therapeutic and for Solid Organ Transplant
Technology: TRaMs are a novel therapeutic tool for immunosuppression during solid organ transplantation that encompasses a pH sensitive, self-assembling nanocarrier with encapsulated rapamycin and a targeting moiety for endothelial cells. TRaMs internalize more rapidly than non-targeted RaMs, suppress biomarkers of EC inflammation and reduce MHC ex...
Published: 4/4/2014   |   Inventor(s): Ann-Marie Broome, Suraj Dixit, Satish Nadig, Carl Atkinson
Category(s): Therapeutic
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