Search Results - satish nadig

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Organ Preconditioning with Mitochondrial Elongating Agents M1/Mdivi1 in Transplantation
M1/Mdivi1 as a novel treatment to reduce immunogenicity in organ transplantationTechnology: Addition of M1 and Mdivi1 drugs in organ preservation solutions can reduce the immunogenicity of the donor organ’s microvascular endothelial cells (ECs), thereby promoting allograft immune tolerance. Inventors at MUSC have found that the use of M1 (a m...
Published: 3/19/2018   |   Inventor(s): Satish Nadig, Carl Atkinson, Danh Tran
Keywords(s):  
Category(s): Therapeutic
Targeted Rapamycin Micelle (TRaM) as a Therapeutic and for Solid Organ Transplant
Technology: TRaMs are a novel therapeutic tool for immunosuppression during solid organ transplantation that encompasses a pH sensitive, self-assembling nanocarrier with encapsulated rapamycin and a targeting moiety for endothelial cells. TRaMs internalize more rapidly than non-targeted RaMs, suppress biomarkers of EC inflammation and reduce MHC ex...
Published: 4/4/2014   |   Inventor(s): Ann-Marie Broome, Suraj Dixit, Satish Nadig, Carl Atkinson
Keywords(s):  
Category(s): Therapeutic
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