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Executive Summary Common dental procedures and surgeries require periodontal flap retractation. This includes over 20,000,00 root canals per year where a 20% failure rate is realized in the initial root canal treatment. When engaging in a surgery to repair those that have failed, the surgeon and/or assistant must utilize a tissue retractor device,...

Published: 5/3/2024 | Inventor(s): Joshua Dale

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Category(s): MedTech

Pseudo-Diaphragmatic Expansion Perfusion & Cryopreservation of Intact Viable Tissues

Researchers at MUSC have developed a rapid and reproducible method for the cryopreservation of a variety of tissues, such that when thawed are comparable to freshly resected tissues. To date, analysis has been completed on lung tissue from patients undergoing lobectomy or transplant and prostate tissue. This method involves the pseudo-diaphragmatic...

Published: 1/22/2026 | Inventor(s): John E Baatz, Demetri d. Spyropoulos

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Category(s): MedTech

Kinetic targeting of intravascular triggered drug delivery system

Device for Vascular Filtration of Excess Chemotherapeutic Containing Thermally Sensitive Liposomes via Kinetic TargetingTechnology: Researchers at MUSC have created a device and method that can remove excess chemotherapeutic containing Intravascular Triggered Drug Delivery Systems (IVDDSs) that are utilized in localized drug treatment, thus greatly...

Published: 3/27/2025 | Inventor(s): Dieter Haemmerich, Anjan Motamarry

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Category(s): MedTech

Biopsy Clip Metal Detector to Aid Breast Surgery

This metal detector localizes biopsy clips (e.g. titanium) placed at the site of breast tissue biopsies. The device is a handheld metal detector that can be inserted into a surgical incision to help locate small markers without an invasive procedure to insert a localizing wire, radioactive seed, or other localization technologies. The device is able...

Published: 5/22/2025 | Inventor(s): Nancy DeMore, Delphine Dean, Scott Slaney, Joseph Wilson III, Cody Jordan, Melissa McCullough

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Category(s): MedTech

Motion-Activated, Closed-loop Non-invasive Vagus Nerve Stimulation as a Neurorehabilitation Tool

Technology: Surgeons and researchers at MUSC have created a non-invasive, motion-activated, closed-loop vagus nerve simulation (VNS) device that enhances neuroplasticity to accelerate motor restoration in post-stroke rehabilitation. The device couples VNS with limb motion to provide stimulation simultaneously with movement, enhancing the effects of...

Published: 1/23/2026 | Inventor(s): Bashar Badran, Mark George

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Category(s): MedTech

A novel Ergonomic Face Mask for Manual Ventilation

Technology: Surgeons and researchers at MUSC have created a new design for a ventilation mask (Figure 1) that features a more ergonomic, less visually obstructive grip. The neck of the ventilation mask is located closer to the top of the patient’s head, the anterior surface is concave, and there is a grooved pad on the mask. This trio of features...

Published: 4/27/2023 | Inventor(s): R. David Warters, Robert Dickie

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Category(s): MedTech

Minimally Invasive Subdural Evacuating System (MISES™) for Treating Subdural Hematomas

Technology: MUSC inventors and surgeons have developed an advanced minimally invasive subdural evacuating system (MISES™) that addresses many of the challenges of treating subdural hematomas. MISES™ improves on the current standard of care, the subdural evacuating port system, with a number of features that are designed to improve outcomes,...

Published: 5/2/2024 | Inventor(s): Stephen Kalhorn, Ryan Kellogg, Joseph Ruscito

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Category(s): MedTech

Looped Skin Hooks "Roberts Retractor"

Technology: Surgeons and researchers at MUSC have created a new design for a skin hook that enables a gripping orientation more clinician-friendly from the traditional pencil-grip style. The design terminates in a loop that may fit around a finger. This loop design may reduce fatigue and permit a single hand to hold more than one skin hook. While introducing...

Published: 6/26/2025 | Inventor(s): Matthew Roberts, Andrea Abbott

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Category(s): MedTech

A system for enhancing feeding behavior in neonates

A system for enhancing feeding behavior in neonates Technology: Researchers at MUSC have created a method and device for improving and accelerating learned feeding behaviors in neonates via vagus nerve stimulation that is coordinated with the neonate’s natural feeding efforts, potentially supporting earlier discharge from the hospital, lower...

Published: 12/10/2024 | Inventor(s): Dorothea Jenkins, Mark George, Bashar Badran, William DeVries, Philipp Summers, Morgan Dancy, Daniel Cook, Georgia Mappin

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Category(s): MedTech

Custom 3D Printed Dental Surgical Guides with Internally Irrigated Cooling Canals for Temperature Reduction during Dental Implants and Endodontics

Custom 3D Printed Dental Surgical Guides with Internally Irrigated Cooling Canals for Temperature Reduction during Dental Implants and EndodonticsTechnology: Researchers at MUSC have created a method and device that revolutionizes dental implants and endodontic therapies by providing custom 3D printed implant guides with custom 3D irrigated cooling...

Published: 10/6/2025 | Inventor(s): Walter Renne, Zachery Evans

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Category(s): MedTech

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