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Plasma Biomarkers for Predicting Recurrence of Atrial Fibrillation Following Cardioversion

The inventors have developed a panel of biomarkers, including various matrix metalloproteinases (MMPs) and tissue inhibitor matrix metalloproteinases (TIMPs), which can determine patients at risk for recurrent atrial fibrillation (AF). These biomarkers can pre-emptively detect treatment failure for cardioversion activities. These biomarkers can be detected...

Published: 3/22/2023 | Inventor(s): Rupak Mukherjee, Michael Gold, Francis Spinale

Keywords(s): cardiovascular, diagnostic

Category(s): BioPharma

Biomarkers for the Detection and Monitoring of Coronary Artery Disease

Technology: The inventors have developed a methodology that has been robustly validated (~800 patients) to accurately and reliably measure Ox-LDL, AGE-LDL and other modified LDLs circulating in bound/immune-complex (IC) form. The method involves isolation of IC from blood samples and fractionation of the isolated IC in order to separate modified forms...

Published: 3/22/2023 | Inventor(s): Maria Lopes-Virella, Gabriel Virella

Keywords(s): cardiovascular, diagnostic

Category(s): BioPharma

Biomarker for the Detection and Monitoring of Bladder Cancer

The inventors have developed a biomarker application based on thromboxane receptor β (TPβ), which identifies patients with various stages of bladder cancers (invasive, superficial, or metastatic). TPβ proteins are overexpressed in common bladder tumor tissue but not normal human cells. Human urine samples of patients positive for various...

Published: 12/20/2023 | Inventor(s): Omar Moussa, Dennis Watson, Perry Halushka

Keywords(s): cancer, diagnostic, genitourinary

Category(s): BioPharma