Search Results - perry+halushka

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Endothelial Progenitor Cell-Derived Exosomes as a Novel Therapeutic in Sepsis
Technology: MUSC researchers have developed a novel therapy to treat sepsis and Acute Respiratory Distress Syndrome (ARDS) using endothelial progenitor cell-derived (EPC) exosomes, which reduced lung and organ injury, inflammation response, and increased survival rate in a mouse model. Data gathered showed that in a sepsis model, IV administration of...
Published: 8/20/2019   |   Inventor(s): Hongkuan Fan, Andrew Goodwin, Perry Halushka, James Cook, Yue Zhou, Pengfei Li
Category(s): Therapeutic
Therapeutic Approach for Combination Cancer Treatments Using Compounds that Block or Interfere with Thromboxane Signaling Pathways
Technology: Inventors at MUSC have developed methods for treatment of cancers, particularly bladder, genitourinary, or pancreatic cancers that involve overexpression of thromboxane receptor β (TP-β). Compounds that block the synthesis of thromboxane A2 or thromboxane A2 signaling pathway alone, or in combination with standard chemotherapy...
Published: 2/13/2015   |   Inventor(s): Omar Moussa, Dennis Watson, Perry Halushka
Keywords(s): cancer, genitourinary
Category(s): Therapeutic
Biomarker for the Detection and Monitoring of Bladder Cancer
The inventors have developed a biomarker application based on thromboxane receptor β (TPβ), which identifies patients with various stages of bladder cancers (invasive, superficial, or metastatic). TPβ proteins are overexpressed in common bladder tumor tissue but not normal human cells. Human urine samples of patients positive for various...
Published: 3/27/2011   |   Inventor(s): Omar Moussa, Dennis Watson, Perry Halushka
Keywords(s): cancer, diagnostic, genitourinary
Category(s): Diagnostic
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