Search Results - cancer

3 Results Sort By:
MUSC Oncology Therapeutics
MUSC Oncology Therapeutics: Liposomal Delivery of Encapsulated Therapeutics to Treat Pediatric Brain Tumors LSD1 Protein Inhibitors as Epigenetic Modulators Cyclic Peptide Inhibitors of Lysine-Specific Demethylase 1 (LSD1) Chaperone-based...
Published: 2/7/2023   |   Inventor(s):  
Keywords(s): cancer
Category(s): BioPharma
Cyclic Peptide Inhibitors of Lysine-Specific Demethylase 1 (LSD1)
Technology: Researchers at MUSC have used a ligand-based approach to design and synthesize a series of cyclic peptides that are effective inhibitors of LSD1, and have greater stability to proteolytic degradation than their linear homologues. Cyclic peptide 9 inhibits LSD1 in vitro with a Ki value of 385 nM, and has antitumor activity in MCF-7 and Calu-6...
Published: 4/25/2023   |   Inventor(s): Patrick Woster, Isuru Kumarasinghe
Keywords(s): cancer
Category(s): BioPharma
Biomarker for the Detection and Monitoring of Bladder Cancer
The inventors have developed a biomarker application based on thromboxane receptor β (TPβ), which identifies patients with various stages of bladder cancers (invasive, superficial, or metastatic). TPβ proteins are overexpressed in common bladder tumor tissue but not normal human cells. Human urine samples of patients positive for various...
Published: 12/20/2023   |   Inventor(s): Omar Moussa, Dennis Watson, Perry Halushka
Keywords(s): cancer, diagnostic, genitourinary
Category(s): BioPharma
© 2024. All Rights Reserved. Powered by Inteum