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MUSC Other Therapeutics: Novel Biofabrication Techniques for the Implementation of Intrinsic Tissue Geometries to an In Vitro Collagen Hydrogelhttp://musc.technologypublisher.com/technology/17788 Targeted Rapamycin Micelle (TRaM) as a Therapeutic in Solid Organ Transplanthttp://musc.technologypublisher.com/technology/14993 Use of Double Stranded...

Published: 2/7/2023 | Inventor(s):

Keywords(s): autoimmune, infectious, inflammation, renal, veterinary

Category(s): BioPharma

High-Throughput Screening Assay for Novel Inhibitors of Penicillin Binding Proteins

Researchers at MUSC have developed a high-throughput assay that uses fluorescence polarization (FP) to distinguish the fluorescent penicillin, Bocillin-FL, in free or PBP-bound form. The assay can be used to identify new compounds that inhibit penicillin binding proteins (PBPs), which are proven targets for β-lactam antibiotics. This assay was...

Published: 9/25/2014 | Inventor(s): Christopher Davies, Alena Fedarovich, Yuri Peterson

Keywords(s): infectious

Category(s): Therapeutic