Search Results - yuri peterson

4 Results Sort By:
5HT1F receptor ligands that induce mitochondrial biogenesis
Technology: MUSC investigators have synthesized new chemical entity analogues for 5HT1F receptors. These structurally unique novel chemical entities act as agonists to the serotonin class-1F (5HT1F) receptors and were found to be potent inducers of mitochondrial biogenesis (MB) in vitro. Also, several of the compounds were tested and found to indu...
Published: 6/27/2018   |   Inventor(s): Christopher Lindsey, Craig Beeson, Rick Schnellmann, Yuri Peterson
Keywords(s):  
Category(s): Therapeutic
High-Throughput Screening Assay for Novel Inhibitors of Penicillin Binding Proteins
Researchers at MUSC have developed a high-throughput assay that uses fluorescence polarization (FP) to distinguish the fluorescent penicillin, Bocillin-FL, in free or PBP-bound form. The assay can be used to identify new compounds that inhibit penicillin binding proteins (PBPs), which are proven targets for β-lactam antibiotics. This assay wa...
Published: 5/20/2014   |   Inventor(s): Christopher Davies, Alena Fedarovich, Yuri Peterson
Keywords(s): infectious
Category(s): Therapeutic
MitoMoby Mitochondrial Morphology Analysis Software
MitoMoby is a high throughput and high content microscopic method for the analysis of mitochondrial morphology (MM) and membrane potential. MitoMoby delineates a procedure for MM analysis using the R platform for data analysis, annotation, and image registration and GE INCell Investigator (specifically, the GE INCell Developer Toolbox package) plat...
Published: 3/19/2014   |   Inventor(s): Craig Beeson, Baerbel Rohrer, Anthony Leonard, Rick Schnellmann, Bethany Wolf, Jaime Speiser, Robert Cameron, Yuri Peterson
Keywords(s):  
Category(s): Software, Research Tool
DotQuanta Endosome Quantifying Software
Researchers at MUSC have configured a robust, platform-independent algorithm for use of real-time quantification of receptor endosome formation, agonist mobilization, co-localization, areas, and shapes. The algorithm works by segmenting the cells, localizing fluorescently stained nuclei to the segmented outlines, counting the number of small object...
Published: 10/21/2013   |   Inventor(s): Yuri Peterson, Sherwin Soltani, Kathryn Appleton, Anthony Leonard
Keywords(s):  
Category(s): Software, Research Tool
© 2019. All Rights Reserved. Powered by Inteum